Combating Superbug Without Antibiotic on a Postamputation Wound in a Patient With Diabetic Foot. (March 2016)

• Record Type: Journal Article
• Authors: Sun, Shuyao; Wang, Chun; Chen, Dawei; Cen, Shiqiang; Lv, Xiaoju; Wen, Xiaorong; Liu, Min; Lu, Wusheng; Zhao, Jichun; Ran, Xingwu
• Is Part Of: International journal of lower extremity wounds. Volume 15:Number 1(2016:Mar.)
• Page Start: 74
• Page End: 77
• Publication Date: 2016-03
• Subjects: autologous platelet-rich gel -- diabetic foot -- multidrug-resistant bacterial infection -- negative pressure wound therapy; Leg -- Wounds and injuries -- Periodicals; Wounds and injuries -- Prevention -- Periodicals; Leg -- Ulcers -- Periodicals; Wound healing -- Periodicals; 617.584
• DOI: 10.1177/1534734615595736
• Languages: English
• ISSNs: 1534-7346

Abstract

Diabetic foot is a kind of limb- and life-threatening complication that is difficult to treat with conventional therapy, especially when accompanied with peripheral arterial insufficiency and severe infection. We present a diabetic patient with a postamputation wound infected by multidrug-resistant Acinetobacter baumannii/haemolyticus, which was resistant to almost all antibiotics. As the clinical response to antimicrobial therapy was poor, antibiotic was discontinued. Autologous platelet-rich gel with anticoagulation, negative pressure wound therapy, and improvement of microcirculation were used successfully to eradicate infection of the superbug and achieve final wound closure.