Serum 25-OH Vitamin D Level in Psoriatic Patients and Comparison With Control Subjects. Issue 3 (May 2016)

• Record Type: Journal Article
• Authors: Maleki, Masoud; Nahidi, Yalda; Azizahari, Sahar; Meibodi, Naser Tayyebi; Hadianfar, Ali
• Is Part Of: Journal of cutaneous medicine and surgery. Volume 20:Issue 3(2016:May/Jun.)
• Page Start: 207
• Page End: 210
• Publication Date: 2016-05
• Subjects: psoriasis -- serum vitamin D -- Psoriasis Area and Severity Index (PASI); Dermatology -- Periodicals; Skin -- Diseases -- Treatment -- Periodicals; Skin -- Surgery -- Periodicals; Dermatology -- Canada -- Periodicals; Skin -- Diseases -- Treatment -- Canada -- Periodicals; Skin -- Surgery -- Canada -- Periodicals; 616.5005
• DOI: 10.1177/1203475415622207
• Languages: English
• ISSNs: 1203-4754

Abstract

Background: Vitamin D has been shown to have immunomodulatory effects, and previous studies have proposed a role of vitamin D deficiency in multiple autoimmune diseases, including psoriasis. Objectives: The aim of this study was to investigate serum vitamin D levels in psoriatic patients and compare them with levels in controls. Methods: This study was carried out in 50 psoriasis patients. Serum vitamin D was measured by enzyme-linked immunosorbent assay. Results: The mean serum vitamin D levels in psoriatic patients and controls were 14.92 ± 6.31 and 12.52 ± 4.54 ng/mL, respectively. The difference was not statistically significant ( P = .06). The prevalence of vitamin D deficiency (<20 ng/mL) was 84.0% in psoriatic patients and 93.0% in controls ( P = .21). Conclusions: Most of the patients with psoriasis had vitamin D deficiency, which may have contributed to the evolution of their psoriasis. However, considering the high prevalence of vitamin D deficiency in Iran, no difference was noted between the psoriatic patients and the controls.