National trends and outcomes of hospitalizations for pulmonary hypertension in Spain (2001–2014). (15th July 2018)

• Record Type: Journal Article
• Authors: de-Miguel-Díez, Javier; López-de-Andrés, Ana; Hernandez-Barrera, Valentin; Jimenez-Trujillo, Isabel; de-Miguel-Yanes, Jose María; Mendez-Bailón, Manuel; Jimenez-Garcia, Rodrigo
• Is Part Of: International journal of cardiology. Volume 263(2018)
• Page Start: 125
• Page End: 131
• Publication Date: 2018-07-15
• Subjects: Pulmonary hypertension -- Hospitalization -- Comorbidity -- In-hospital mortality -- Cost; Cardiology -- Periodicals; Electronic journals; 616.12
• DOI: 10.1016/j.ijcard.2018.04.026
• Languages: English
• ISSNs: 0167-5273

Abstract

Abstract: Objective: To assess changes in incidence, diagnostic procedures, comorbidity profiles, length of hospital stay (LOHS), costs, and in-hospital mortality (IHM) for patients hospitalized with pulmonary hypertension (PH). Methods: We included patients hospitalized with PH in Spain from 2001 to 2014. The data were collected from the National Hospital Discharge Database. Results: We included 644, 436 discharges (43.31% males and 56.09% females) admitted for primary PH (8.34%) or secondary PH (91.66%). The crude incidence rate increased from 58.67 to 148.32 hospitalizations per 100, 000 inhabitants between 2001 and 2002 and 2013–2014 ( p < 0.001). The percentage of patients with a Charlson comorbidity index ≥2 was 27.87% in 2001–2002, increasing to 47.02% in 2013–2014 ( p < 0.001). IHM was 8.77%, with a reduction in the value yielded by the multivariable analysis between 2009 and 2010 and 2013–2014. Median LOHS was 9 ± 9 days in 2001–2002, which decreased to 7 ± 8 days in 2013–2014 ( p < 0.001). The mean cost per patient increased from €3352.4 ± €1495 in the period 2001–2002 to €4198.94 ± €1287.96 in 2013–2014 ( p < 0.001). Conclusions: Despite the increase over time in hospital admissions for PH, associated comorbidity, and costs, LOHS and IHM decreased, suggesting that the management of PH-related hospitalizations improved in Spain during the study period. Highlights: The incidence of pulmonary hypertension hospitalizations has increased from the period 2001–2002 to 2013–2014 in Spain. The overall in-hospital mortality was 8.77%, with a reduction in the multivariable analysis over the study period. The mean cost per patient increased from 3352€ in the period 2001–2002 to 4199€ in 2013–2014. These results suggest that the management of PH-related hospitalizations has improved in Spain during the study period.