Agenesis of Corpus Callosum and Frontotemporal Dementia: A Casual Finding?. (June 2015)

• Record Type: Journal Article
• Authors: Calabrò, Rocco Salvatore; Spadaro, Letteria; Marra, Angela; Balletta, Tina; Cammaroto, Simona; Bramanti, Placido
• Is Part Of: American journal of Alzheimer's disease & other dementias. Volume 30:Number 4(2015)
• Page Start: 375
• Page End: 379
• Publication Date: 2015-06
• Subjects: dementia -- corpus callosum -- agenesis -- aging; Alzheimer's disease -- Periodicals; Dementia -- Periodicals; Alzheimer's disease -- Patients -- Care -- United States -- Periodicals; 616.83
• DOI: 10.1177/1533317514549410
• Languages: English
• ISSNs: 1533-3175

Abstract

Agenesis of corpus callosum (AgCC) is a congenital malformation characterized by total or partial absence of corpus callosum with a good neuropsychological profile. Frontotemporal dementia (FTD) is the third most common cause of cortical dementia, and it is characterized by alterations in personality and social relationship, often associated with deficits in attention, abstraction, planning, and problem solving. Herein, we report a case of a 73-year-old woman presenting with FTD associated with primary AgCC. The possible "causal or casual" relationship between these 2 different conditions should be investigated in large prospective studies.