P.04.6 PRIMARY HUMAN BILIARY TREE STEM/PROGENITOR CELLS (HBTSCS) EXPOSED TO MICROENVIRONMENTAL FACTORS SHOWED PROLIFERATION, EPITHELIAL-MESENCHYMAL TRANSITION (EMT) AND SENESCENCE, RECAPITULATING THE PATHOLOGICAL FEATURES TYPICAL OF HUMAN CHOLANGIOPATHIES. Issue 2 (15th March 2018) - Costantini, D.; Cardinale, V.; Carpino, G.; Nevi, L.; Di Matteo, S.; Safarikia, S.; Melandro, F.; Berloco, P.B.; Gaudio, E.; Alvaro, D.