High-performance liquid chromatography mass spectrometry of gold and alloy clusters protected by hydrophilic thiolates. Issue 4 (1st December 2017)

• Record Type: Journal Article
• Authors: Niihori, Yoshiki; Shima, Daisuke; Yoshida, Kana; Hamada, Kota; Nair, Lakshmi V.; Hossain, Sakiat; Kurashige, Wataru; Negishi, Yuichi
• Is Part Of: Nanoscale. Volume 10:Issue 4(2018)
• Page Start: 1641
• Page End: 1649
• Publication Date: 2017-12-01
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/c7nr07840d
• Languages: English
• ISSNs: 2040-3364

Abstract

Abstract : This study has succeeded in high-performance liquid chromatography mass spectrometry of hydrophilic thiolate-protected gold and alloy clusters by finding two suitable and versatile HILIC columns. Abstract : In this work, we found two hydrophilic interaction liquid chromatography (HILIC) columns for high-performance liquid chromatography (HPLC) suitable for the high-resolution separation of hydrophilic metal clusters. The mass distributions of the product mixtures of hydrophilic metal clusters were evaluated via HPLC mass spectrometry (LC/MS) using these HILIC columns. Consequently, we observed multiple clusters that had not been previously reported for glutathionate (SG)-protected gold clusters (Au n (SG) m ). Additionally, we demonstrated that Au n − x M x (SG) m alloy clusters (M = Ag, Cu, or Pd) in which part of the Au in the Au n (SG) m cluster is replaced by a heteroelement can be synthesized, similar to the case of hydrophobic alloy clusters. It is easy to evaluate the mass distributions of hydrophilic metal clusters using this method. Thus, remarkable progress in the synthesis techniques of hydrophilic metal clusters through the use of this method is anticipated, as is the situation for hydrophobic metal clusters.