Effects of Material Properties on Bacterial Adhesion and Biofilm Formation. (August 2015)

• Record Type: Journal Article
• Authors: Song, F.; Koo, H.; Ren, D.
• Is Part Of: Journal of dental research. Volume 94:Number 8(2015:Aug.)
• Page Start: 1027
• Page End: 1034
• Publication Date: 2015-08
• Subjects: bacteria -- biomaterials -- dental implants -- infection control -- dentistry -- biofouling; Dentistry -- Periodicals; Dentistry -- Social aspects -- Periodicals; Dentistry -- Periodicals; Research -- Periodicals; 617.6005
• DOI: 10.1177/0022034515587690
• Languages: English
• ISSNs: 0022-0345

Abstract

Adhesion of microbes, such as bacteria and fungi, to surfaces and the subsequent formation of biofilms cause multidrug-tolerant infections in humans and fouling of medical devices. To address these challenges, it is important to understand how material properties affect microbe-surface interactions and engineer better nonfouling materials. Here we review the recent progresses in this field and discuss the main challenges and opportunities. In particular, we focus on bacterial biofilms and review the effects of surface energy, charge, topography, and stiffness of substratum material on bacterial adhesion. We summarize how these surface properties influence oral biofilm formation, and we discuss the important findings from nondental systems that have potential applications in dental medicine.