Visible Light Activated Radical Denitrative Benzoylation of β‐Nitrostyrenes: A Photocatalytic Approach to Chalcones. Issue 7 (16th February 2018)

• Record Type: Journal Article
• Authors: Tripathi, Shubhangi; Kapoor, Ritu; Yadav, Lal Dhar S.
• Is Part Of: Advanced synthesis & catalysis. Volume 360:Issue 7(2018)
• Page Start: 1407
• Page End: 1413
• Publication Date: 2018-02-16
• Subjects: C−C bond formation -- organic catalysis -- photochemistry -- radicals -- synthetic methods -- visible light; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201701559
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A metal‐free, convenient photocatalytic approach to chalcones from β ‐nitrostyrenes and benzaldehydes via a radical denitrative benzoylation pathway is reported. The salient features of the protocol include the utilization of visible light as an inexpensive and ecosustainable energy source, N ‐hydroxyphthalimide (NHPI) as a reusable organophotocatalyst and acetonitrile as an acceptable green solvent to afford chalcones in excellent yields at room temperature in a one‐pot procedure. Notably, this is the first application of β ‐nitrostyrenes as readily available substrates for chalcone synthesis and the first example of photocatalysis in this field. Abstract :