4-Hydroxybenzoic acid for multiple system atrophy?. (May 2018)

• Record Type: Journal Article
• Authors: Distelmaier, Felix
• Is Part Of: Parkinsonism & related disorders. Volume 50(2018)
• Page Start: 119
• Page End: 120
• Publication Date: 2018-05
• Subjects: Therapy -- COQ2 -- Coenzyme Q10 -- Neurodegeneration; Parkinson's disease -- Periodicals; Movement disorders -- Periodicals; Movement Disorders -- Periodicals; Nerve Degeneration -- Periodicals; Nervous System Diseases -- Periodicals; Parkinson Disease -- Periodicals; Tremor -- Periodicals; Parkinson, Maladie de -- Périodiques; Parkinson's disease; 616.833
• DOI: 10.1016/j.parkreldis.2018.01.019
• Languages: English
• ISSNs: 1353-8020

Abstract

Abstract: Increasing evidence supports a link between multiple system atrophy and coenzyme Q10 (CoQ10 ) biosynthesis. However, so far this knowledge was not translated into tangible benefits for affected patients. Poor bioavailability of oral CoQ10 might constitute a major problem. Current research suggests that 4-hydroxybenzoic acid might constitute an interesting alternative treatment option.