A mandibular lesion revealing multiple myeloma. (20th October 2017)

• Record Type: Journal Article
• Authors: Benjelloun, L.; Dghoughi, S.; Taleb, B.
• Is Part Of: Oral surgery. Volume 11:Number 2(2018:May)
• Page Start: 157
• Page End: 162
• Publication Date: 2017-10-20
• Subjects: jaw -- malignant plasma cells -- multiple myeloma -- plasmacytoma; Mouth -- Surgery -- Periodicals; 617.522059
• DOI: 10.1111/ors.12316
• Languages: English
• ISSNs: 1752-2471

Abstract

Abstract: Multiple myeloma is a disease resulting from clonal proliferation of plasma cells. It is the most common primary bone malignancy. The most common clinical signs and symptoms of multiple myeloma include bone pain, fatigue, anaemia, infectious diseases and it is characterized by multiple punched‐out radiolucent lesions. Jaw lesions may be present in the advanced stages of multiple myeloma. Rarely, the oral and maxillofacial lesions can be the first manifestation of the disease. We report a rare case of a 55‐year‐old man who presented with a left mandibular swelling of a duration of 2 months. The panoramic radiograph showed a large destructive radiolucency in the left molar region and the angle of the left mandible. A biopsy was performed and revealed the diagnosis of a plasmocytoma. Further investigations of the patient revealed other osteolytic lesions in other bones, confirming the diagnosis of multiple myeloma.