Circulating Tumor Cells: DNA‐Templated Magnetic Nanoparticle‐Quantum Dot Polymers for Ultrasensitive Capture and Detection of Circulating Tumor Cells (Adv. Funct. Mater. 14/2018). (6th April 2018)

• Record Type: Journal Article
• Authors: Li, Zhi; Wang, Ganglin; Shen, Yi; Guo, Nannan; Ma, Nan
• Is Part Of: Advanced functional materials. Volume 28:Number 14(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-04-06
• Subjects: aptamers -- circulating tumor cells -- DNA -- magnetic nanoparticles -- quantum dots; Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201870089
• Languages: English
• ISSNs: 1616-301X

Abstract

Abstract : In article number1707152, Nan Ma and co‐workers develop a new class of DNA‐templated magnetic nanoparticle‐quantum dot‐aptamer polymers (MQAPs) for ultrasensitive capture and detection of circulating tumor cells from human blood with high capture efficiency and purity approaching 80%. These MQAPs exhibit amplified magnetic response, extraordinary binding selectivity for target cells, and ultra‐bright quantum dot photoluminescence for single cell detection and phenotype profiling.