Rhodium(III)‐Catalyzed [2+2+2] Cyclotrimerization of Diynes with Maleic Anhydrides as Alkyne Equivalents. Issue 14 (7th April 2015)

• Record Type: Journal Article
• Authors: Matsuda, Takanori; Suzuki, Kentaro
• Is Part Of: European journal of organic chemistry. Issue 14(2015)
• Page Start: 3032
• Page End: 3035
• Publication Date: 2015-04-07
• Subjects: Synthetic methods -- Homogeneous catalysis -- Rhodium -- Cyclotrimerization -- Anhydrides -- Alkynes; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201500252
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: Substituted maleic anhydrides function as synthetic equivalents of alkynes in a rhodium(III)‐catalyzed reaction with 1, 6‐diynes to achieve a formal [2+2+2] cyclotrimerization. This approach is useful for reactions involving alkynes with low boiling points or severe ring strain. Hard‐to‐access [2+2+2] cycloadducts are available through this new cycloaddition strategy by employing easy‐to‐handle alkyne equivalents. Abstract : Substituted maleic anhydrides act as alkyne equivalents in a rhodium(III)‐catalyzed reaction with 1, 6‐diynes to achieve a formal [2+2+2] cyclotrimerization.