NBu4NI‐Catalyzed α‐Benzoxylation of Ketones with Terminal Aryl Alkenes. Issue 14 (7th April 2015)

• Record Type: Journal Article
• Authors: Mondal, Buddhadeb; Sahoo, Subas Chandra; Pan, Subhas Chandra
• Is Part Of: European journal of organic chemistry. Issue 14(2015)
• Page Start: 3135
• Page End: 3140
• Publication Date: 2015-04-07
• Subjects: Synthetic methods -- Ketones -- Alkenes -- Radicals; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.201500233
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract: A metal‐free protocol for the α‐benzoxylation of ketones has been developed by using terminal aryl alkenes as an arylcarboxy surrogate. Moderate to good yields were attained for a variety of propiophenones and acetophenones by using tetra‐ n ‐butylammonium iodide (TBAI) as the catalyst and tert ‐butyl hydroperoxide (TBHP) as the oxidant under ambient reaction conditions. Abstract : An efficient synthesis for the α‐benzoxylation of aryl ketones has been developed by using terminal aryl alkenes as the arylcarboxy surrogate. The products were obtained in moderate to good yields for a broad scope of substrates. Tetra‐ n ‐butylammonium iodide (TBAI) and tert ‐butyl hydroperoxide (TBHP) were employed as the catalyst and oxidant, respectively.