Novel biflavonoids from Cephalotaxus oliveri Mast. (April 2018)

• Record Type: Journal Article
• Authors: Ren, Dai; Meng, Fan-Cheng; Liu, Hui; Xiao, Tong; Lu, Jin-Jian; Lin, Li-Gen; Chen, Xiu-Ping; Zhang, Qing-Wen
• Is Part Of: Phytochemistry letters. Volume 24(2018)
• Page Start: 150
• Page End: 153
• Publication Date: 2018-04
• Subjects: Cephalotaxus oliveri -- Biflavonoid -- Flavonoid -- Alkaloid -- Umcephabiflovin -- α-Glucosidase inhibitory effect; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2018.02.005
• Languages: English
• ISSNs: 1874-3900

Abstract

Graphical abstract: Three new biflavonoids, including umcephabiflovins A (1 ) and B (2 ) as well as S -taiwanhomoflavone-B (3 ), together with fourteen known compounds (4–17 ) were isolated from Cephalotaxus oliveri Mast. The flavonoids showed α-glucosidase inhibitory effects. Highlights: Three new biflavonoids were isolated from Cephalotaxus oliveri . Seven known flavonoids and seven alkaloids were also isolated. Their structures were determined by spectroscopic analysis. Their absolute configurations were elucidated through CD spectra. The flavonoids showed α-glucosidase inhibitory effects. Abstract: Three new biflavonoids, umcephabiflovin A (1 ), umcephabiflovin B (2 ), and S -taiwanhomoflavone-B (3 ), together with seven known flavonoids (4–10 ) and seven known alkaloids (11 –17 ), were isolated from the twigs of Cephalotaxus oliveri Mast. The flavonoids were found to inhibit α-glucosidase activity.