A new equation to predict peak VO2 in obese patients during cardiopulmonary exercise testing. (14th July 2017)

• Record Type: Journal Article
• Authors: Barbosa, Alan Carlos Brisola; Sperandio, Evandro Fornias; Gonze, Bárbara de Barros; Spina, Giovanna Domingues; Arantes, Rodolfo Leite; Gagliardi, Antônio Ricardo de Toledo; Romiti, Marcello; Dourado, Victor Zuniga
• Is Part Of: Clinical physiology and functional imaging. Volume 38:Number 3(2018:May)
• Page Start: 462
• Page End: 467
• Publication Date: 2017-07-14
• Subjects: obesity -- oxygen consumption -- physical exertion -- physical fitness -- stress test; Physiology, Pathological -- Periodicals; Diagnostic imaging -- Periodicals; 612
• DOI: 10.1111/cpf.12438
• Languages: English
• ISSNs: 1475-0961

Abstract

Summary: We aimed to develop an equation to predict peak VO2 in obese subjects undergoing CPET. In addition, we evaluated and compared three published equations. We randomized 346 obese subjects undergoing CPET into a group for developing the equation ( n = 272) and a group for cross‐validation ( n = 74), compared through the Bland and Altman method. Height, sex and age were responsible for 85·5% of total variability of the peak VO2. Additional 1% and 0·7% of the variability were, respectively, explained by physical inactivity and diabetes. The equation devised was as follows: peak VO 2 ml min − 1 = − 677 · 8 + ( 2135 · 9 × height m ) + ( 706 · 8 × sex males = 1 ; females = 0 ) − ( 15 · 5 × age years ) − ( 161 · 1 × physical inactivity yes = 1 ; no = 0 ) − ( 176 · 3 × diabetes yes = 1 ; no = 0 ) . The mean difference between the estimated and measured peak VO2 was 7 ml min −1, with a 23·9% bias. Published equations overestimated the peak VO2 by 35·3%, 49·1% and 46·2% bias. The equation developed in this study performed better in predicting peak VO2 in obese adults improving ramp protocol design and CRF evaluations in obese subjects.