Mediastinal follicular dendritic cell sarcoma with paraneoplastic pemphigus. (July 2015)

• Record Type: Journal Article
• Authors: Chow, Simon CY; Yeung, Eugene CL; Ng, Calvin SH; Wong, Randolph HL; Fai To, Ka; Wan, Innes YP
• Is Part Of: Asian cardiovascular & thoracic annals. Volume 23:Number 6(2015)
• Page Start: 732
• Page End: 734
• Publication Date: 2015-07
• Subjects: Dendritic cell sarcoma -- follicular -- mediastinal neoplasms -- paraneoplastic syndromes -- pemphigus; Heart -- Diseases -- Asia -- Periodicals; Heart -- Diseases -- Pacific Area -- Periodicals; Heart -- Diseases -- Periodicals; Heart -- Surgery -- Asia -- Periodicals; Heart -- Surgery -- Pacific Area -- Periodicals; Heart -- Surgery -- Periodicals; Chest -- Surgery -- Asia -- Periodicals; Chest -- Surgery -- Pacific Area -- Periodicals; Chest -- Surgery -- Periodicals; 617.412
• DOI: 10.1177/0218492314561501
• Languages: English
• ISSNs: 0218-4923

Abstract

Follicular dendritic cell sarcoma is a rare neoplasm of immune accessory cells. It occurs primarily in lymph nodes. Occurrences in the mediastinum are rarely reported. Diagnosis and management of follicular dendritic cell sarcoma remain unclear, and it is an under-recognized clinical entity. Only a few cases of paraneoplastic pemphigus as the first presentation of follicular dendritic cell sarcoma have been reported. We report an unusual case of follicular dendritic cell sarcoma of the anterior mediastinum, presenting as paraneoplastic pemphigus in a 62-year-old man. Typical histological features confirmed the diagnosis of follicular dendritic cell sarcoma, and surgical resection was successfully performed.