Critical-Size Bone Defects: Is There a Consensus for Diagnosis and Treatment?. (March 2018)

• Record Type: Journal Article
• Authors: Nauth, Aaron; Schemitsch, Emil; Norris, Brent; Nollin, Zachary; Watson, J. Tracy
• Is Part Of: Journal of orthopaedic trauma. Volume 32(2018)Supplement 1
• Publication Date: 2018-03
• Subjects: bone defect -- critical size -- bone graft substitutes -- infection -- osteomyelitis -- induced membrane -- Masquelet; Orthopedics -- Periodicals; Wounds and injuries -- Periodicals; Orthopedics -- Periodicals; Wounds and Injuries -- therapy -- Periodicals; Periodicals; 617.47044
• DOI: 10.1097/BOT.0000000000001115
• Languages: English
• ISSNs: 0890-5339

Abstract

Abstract : Summary: There is a significant burden of disease associated with bone defects, and their management is challenging. These injuries have a profound clinical and economic impact, and outcomes are limited by high rates of complication and reoperation, as well as poor functional outcomes. There remains a lack of consensus around definitions, reliable models, and best practices for the surgical management of bone defects. The current state of the literature on bone defects is reviewed here, with a focus on defining critical-size bone defect, the use of the induced membrane technique, the role of biologics, and the management of infected bone defects. Abstract : Supplemental Digital Content is Available in the Text.