Waking up muscle stem cells: PI3K signalling is ringing. (26th March 2018)
- Record Type:
- Journal Article
- Title:
- Waking up muscle stem cells: PI3K signalling is ringing. (26th March 2018)
- Main Title:
- Waking up muscle stem cells: PI3K signalling is ringing
- Authors:
- Relaix, Frederic
Machado, Léo - Abstract:
- Abstract : Adult skeletal muscle injury instructs endogenous quiescent stem cells to activate for repair. The pathways involved in this activation remain poorly understood. An elegant study by Wang et al (2018 ) combine mouse molecular genetics with muscle regeneration experiments, cell culture and transcriptomic analysis to show that early activation depends on a PI3K‐mTORC1‐Jun/FoxOs signalling axis. Abstract : Mouse genetics combined with cell culture and transcriptome analyses highlight dependence of satellite cell activation on PI3K–mTORC1–Jun signalling.
- Is Part Of:
- EMBO journal. Volume 37:Number 8(2018)
- Journal:
- EMBO journal
- Issue:
- Volume 37:Number 8(2018)
- Issue Display:
- Volume 37, Issue 8 (2018)
- Year:
- 2018
- Volume:
- 37
- Issue:
- 8
- Issue Sort Value:
- 2018-0037-0008-0000
- Page Start:
- n/a
- Page End:
- n/a
- Publication Date:
- 2018-03-26
- Subjects:
- Molecular biology -- Periodicals
572.805 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.15252/embj.201899297 ↗
- Languages:
- English
- ISSNs:
- 0261-4189
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3733.085000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 6376.xml