Severity of hypoglycaemia and health‐related quality of life, work productivity and healthcare costs in patients with type 2 diabetes in Europe. Issue 2 (19th January 2018)

• Record Type: Journal Article
• Authors: Pawaskar, Manjiri; Witt, Edward A.; Engel, Samuel S.; Rajpathak, Swapnil N.; Iglay, Kristy
• Is Part Of: Endocrinology, diabetes & metabolism. Volume 1:Issue 2(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-01-19
• Subjects: economic burden -- healthcare resource use -- health‐related quality of life -- hypoglycaemia -- type 2 diabetes mellitus -- work productivity; Endocrinology -- Periodicals; Diabetes -- Periodicals; Metabolism -- Periodicals; 616.4
• DOI: 10.1002/edm2.11
• Languages: English
• ISSNs: 2398-9238

Abstract

Summary: Aims: Hypoglycaemia in patients with type 2 diabetes mellitus (T2DM) is associated with poor health outcomes, such as reduced health‐related quality of life (HRQoL). This study aimed to assess the impact of hypoglycaemic events by severity on HRQoL, work productivity and healthcare costs in patients with T2DM. Materials and Methods: European patients with T2DM selected from the National Health and Wellness Survey who were currently receiving pharmacologic therapy were stratified into 3 groups based on the reported history and severity of hypoglycaemic events (no event, nonsevere, severe) experienced in the previous 3 months. Patients' work productivity, HRQoL, healthcare resource use (HCRU) and associated costs were assessed as self‐reported outcomes. Results: Of 1269 patients included in the study, 652 (51.4%) patients had not experienced an event, while 533 (42.0%) and 84 (6.6%) patients had experienced nonsevere and severe hypoglycaemic events, respectively, in the previous 3 months. An increase in hypoglycaemia severity was associated with a decrease in HRQoL, and an increase in HCRU and healthcare costs. Conclusions: The impact of hypoglycaemia varies by severity and has a negative impact on HRQoL and overall HCRU and costs. Abstract : This article describes a study in patients in Europe with type 2 diabetes. It explores the impact of hypoglycaemic events on quality of life, healthcare resource utilization and costs. We showed that an increase in severity of hypoglycaemia resulted in a poorer quality of life, greater healthcare resource utilization and higher costs.