Rapid-Onset Piperacillin-tazobactam Induced Thrombocytopenia. (April 2015)

• Record Type: Journal Article
• Authors: Shaik, Shamsuddin; Kazi, Haseeb A.; Ender, Peter T.
• Is Part Of: Journal of pharmacy practice. Volume 28:Number 2(2015:Apr.)
• Page Start: 204
• Page End: 206
• Publication Date: 2015-04
• Subjects: internal medicine -- drug information; Pharmacy -- Periodicals; Pharmacology -- Periodicals; 615.1
• DOI: 10.1177/0897190014566302
• Languages: English
• ISSNs: 0897-1900

Abstract

Thrombocytopenia can occur from a variety of etiologies. Drug-induced thrombocytopenia is known to occur with beta-lactam medications, but often in the setting of prolonged use. We describe 2 patients who developed rapid-onset thrombocytopenia from piperacillin/tazobactam. Other causes of immediate thrombocytopenia were excluded. These cases describe a rare presentation of rapid-onset thrombocytopenia in a commonly used medication.