Deterministic model of biomolecular networks with stimuli-responsive properties. (May 2015)

• Record Type: Journal Article
• Authors: Creasy, M Austin; Freeman, Eric C; Philen, Michael K; Leo, Donald J
• Is Part Of: Journal of intelligent material systems and structures. Volume 26:Number 8(2015:May)
• Page Start: 921
• Page End: 930
• Publication Date: 2015-05
• Subjects: Bio-inspired -- optimization -- sensor; Smart materials -- Periodicals; Intelligent control systems -- Periodicals; Artificial intelligence -- Periodicals; Matériaux intelligents -- Périodiques; Commande intelligente -- Périodiques; Intelligence artificielle -- Périodiques; 620.11
• DOI: 10.1177/1045389X14536004
• Languages: English
• ISSNs: 1045-389X

Abstract

A deterministic model is presented for predicting the passive and stimuli-responsive characteristics of biomolecular networks. These biomolecular networks consist of multiple bilayer interfaces that can incorporate stimuli-responsive molecules such as peptides and proteins. A model is presented and a lumped parameter method is used to obtain the network equations for several case studies. The model is then utilized to predict the response of a biomolecular network that exhibits rectification behavior due to the presence of voltage-responsive protein incorporated into the interfacial bilayer. This article demonstrates the electric response of systems of biomolecular networks and prompts further research into their use for engineering applications.