Delayed seizure-like activity following analytically confirmed use of previously unreported synthetic cannabinoid analogues. (May 2015)

• Record Type: Journal Article
• Authors: Schep, LJ; Slaughter, RJ; Hudson, S; Place, R; Watts, M
• Is Part Of: Human & experimental toxicology. Volume 34:Number 5(2015:May)
• Page Start: 557
• Page End: 560
• Publication Date: 2015-05
• Subjects: Case report -- synthetic cannabinoids -- seizure -- psychoactive drugs; Toxicology -- Periodicals; 615.9
• DOI: 10.1177/0960327114550886
• Languages: English
• ISSNs: 0960-3271

Abstract

Synthetic cannabinoid use has become widespread, leading to increased burdens on health care providers. Symptoms range from agitation and psychosis to seizures and acute kidney injury. We report a case where a patient was assessed and treated twice within 12 h for seizures following synthetic cannabinoid intoxication. Blood sample determinations showed low concentrations of analogues not previously reported, some of which are legal. Clinicians should be aware that synthetic cannabinoids may cause an array of severe health consequences. Given the ever evolving structure of available analogues, clinicians must also be prepared for other unexpected adverse effects.