Combining photoredox and silver catalysis for azidotrifluoromethoxylation of styrenes. Issue 35 (16th April 2018)

• Record Type: Journal Article
• Authors: Cong, Fei; Wei, Yongliang; Tang, Pingping
• Is Part Of: Chemical communications. Volume 54:Issue 35(2018)
• Page Start: 4473
• Page End: 4476
• Publication Date: 2018-04-16
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c8cc01096j
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : An intermolecular azidotrifluoromethoxylation of styrenes by synergistic visible-light-mediated photoredox and silver catalysis has been reported for the first time. Abstract : The first example of an azidotrifluoromethoxylation of styrenes has been achieved by synergistic visible-light-mediated photoredox and silver catalysis. Trifluoromethyl arylsulfonate (TFMS) and the Zhdankin reagent were used as the trifluoromethoxylation reagent and the azide source, respectively. A good functional group tolerance and mild reaction conditions of this method are applicable to late-stage azidotrifluoromethoxylation of complex small molecules. Furthermore, the mechanistic investigations indicate the single-electron transfer involved in the reaction.