Engineering molecularly imprinted polymers (MIPs) for the selective extraction and quantification of the novel psychoactive substance (NPS) methoxphenidine and its regioisomers. Issue 9 (19th April 2018)

• Record Type: Journal Article
• Authors: Lowdon, J. W.; Alkirkit, S. M. O.; Mewis, R. E.; Fulton, D.; Banks, C. E.; Sutcliffe, O. B.; Peeters, M.
• Is Part Of: Analyst. Volume 143:Issue 9(2018)
• Page Start: 2002
• Page End: 2007
• Publication Date: 2018-04-19
• Subjects: Chemistry, Analytic -- Periodicals; 543
• DOI: 10.1039/c8an00131f
• Languages: English
• ISSNs: 0003-2654

Abstract

Abstract : The first developed Molecularly Imprinted Polymers (MIPs) for the specific detection of methoxphenidine (MXP) and its regioisomers. Abstract : In this communication, we present the first developed Molecularly Imprinted Polymers (MIPs) for the specific detection of a New Psychoactive Substance (NPS); namely, methoxphenidine (MXP) and its regioisomers. Selectivity of the MIP towards MXP is studied by analysing mixtures and an acquired street sample with High Performance Liquid Chromatography coupled to UV detection. The study demonstrates that the engineered polymers selectively extract MXP from heterogeneous samples, which makes for a very powerful diagnostic tool that can detect traces of MXP in complicated NPS samples.