An MTH1-targeted nanosystem for enhanced PDT via improving cellular sensitivity to reactive oxygen species. Issue 34 (11th April 2018)
- Record Type:
- Journal Article
- Title:
- An MTH1-targeted nanosystem for enhanced PDT via improving cellular sensitivity to reactive oxygen species. Issue 34 (11th April 2018)
- Main Title:
- An MTH1-targeted nanosystem for enhanced PDT via improving cellular sensitivity to reactive oxygen species
- Authors:
- Fan, Huanhuan
Zhang, Lili
Hu, Xiaoxiao
Zhao, Zilong
Bai, Huarong
Fu, Xiaoyi
Yan, Guobei
Liang, Li-Hui
Zhang, Xiao-Bing
Tan, Weihong - Abstract:
- Abstract : An MTH1-targeted nanosystem is developed for enhanced PDT through inhibiting MTH1 protein and improving cellular sensitivity to reactive oxygen species. Abstract : Herein, we developed a strategy to attack the cancer cell defense system against reactive oxygen species to improve photodynamic therapy efficacy with a Ce6@MSN@MTH1 siRNA nanosystem, which was demonstrated to improve cellular sensitivity to reactive oxygen species through suppressing MTH1 protein in cancer cells.
- Is Part Of:
- Chemical communications. Volume 54:Issue 34(2018)
- Journal:
- Chemical communications
- Issue:
- Volume 54:Issue 34(2018)
- Issue Display:
- Volume 54, Issue 34 (2018)
- Year:
- 2018
- Volume:
- 54
- Issue:
- 34
- Issue Sort Value:
- 2018-0054-0034-0000
- Page Start:
- 4310
- Page End:
- 4313
- Publication Date:
- 2018-04-11
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8cc01841c ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6346.xml