Gene assembly via one-pot chemical ligation of DNA promoted by DNA nanostructures. Issue 36 (17th April 2018)
- Record Type:
- Journal Article
- Title:
- Gene assembly via one-pot chemical ligation of DNA promoted by DNA nanostructures. Issue 36 (17th April 2018)
- Main Title:
- Gene assembly via one-pot chemical ligation of DNA promoted by DNA nanostructures
- Authors:
- Manuguerra, Ilenia
Croce, Stefano
El-Sagheer, Afaf H.
Krissanaprasit, Abhichart
Brown, Tom
Gothelf, Kurt V.
Manetto, Antonio - Abstract:
- Abstract : A gene was obtained from 14 oligonucleotides self-assembled and chemically ligated in a DNA nanostructure. Abstract : Current gene synthesis methods are driven by enzymatic reactions. Here we report the one-pot synthesis of a chemically-ligated gene from 14 oligonucleotides. The chemical ligation benefits from the highly efficient click chemistry approach templated by DNA nanostructures, and produces modified DNA that is compatible with polymerase enzymes.
- Is Part Of:
- Chemical communications. Volume 54:Issue 36(2018)
- Journal:
- Chemical communications
- Issue:
- Volume 54:Issue 36(2018)
- Issue Display:
- Volume 54, Issue 36 (2018)
- Year:
- 2018
- Volume:
- 54
- Issue:
- 36
- Issue Sort Value:
- 2018-0054-0036-0000
- Page Start:
- 4529
- Page End:
- 4532
- Publication Date:
- 2018-04-17
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8cc00738a ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6346.xml