Bromodimethylsulfonium bromide: an efficient catalyst for one-pot synthesis of 4-phenacylidene flavene derivatives. Issue 19 (6th May 2015)

• Record Type: Journal Article
• Authors: Bhattacharjee, Suchandra; Das, Deb K.; Khan, Abu T.
• Is Part Of: Tetrahedron letters. Volume 56:Issue 19(2015)
• Page Start: 2412
• Page End: 2415
• Publication Date: 2015-05-06
• Subjects: 4-Phenacylidene flavenes -- Salicylaldehydes -- Acetophenones -- Bromodimethylsulfonium bromide; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.03.047
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: The synthesis of 4-phenacylidene flavenes (3) was accomplished by a one-pot pseudo three-component condensation reaction between salicylaldehydes and acetophenones in the presence of 20 mol % of bromodimethylsulfonium bromide (BDMS) in acetonitrile at room temperature. The attractive features of this protocol are: use of organo-catalyst BDMS, simple reaction procedure, high bond-forming efficiency, good yields, and environmentally benign reaction conditions.