Comparative Total and Unbound Pharmacokinetics of Cefazolin Administered by Bolus Versus Continuous Infusion in Patients Undergoing Major Surgery: A Randomized Controlled Trial. Issue 5 (October 2017)

• Record Type: Journal Article
• Authors: Naik, B. I.; Roger, C.; Ikeda, K.; Todorovic, M. S.; Wallis, S. C.; Lipman, J.; Roberts, J. A.
• Is Part Of: Survey of anesthesiology. Volume 61:Issue 5/6(2017)
• Publication Date: 2017-10
• Subjects: Anesthesiology -- Periodicals; 617.96
• DOI: 10.1097/SA.0000000000000336
• Languages: English
• ISSNs: 0039-6206

Abstract

Abstract : (Abstracted from Br J Anaesth, 118(6):876–882, 2017) Administration of the antibiotic cefazolin before incision can reduce the incidence of surgical site infections, thereby reducing postoperative morbidity rates. Following the initial preincision dose, redosing intervals of cefazolin vary between 2 and 5 hours, depending on patient and procedure variables.