Acquired long QT syndrome and torsade de pointes. Issue 4 (30th March 2018)

• Record Type: Journal Article
• Authors: El‐Sherif, Nabil; Turitto, Gioia; Boutjdir, Mohamed
• Is Part Of: Pacing and clinical electrophysiology. Volume 41:Issue 4(2018)
• Page Start: 414
• Page End: 421
• Publication Date: 2018-03-30
• Subjects: electrophysiology -- long QT syndrome -- torsade de pointes; Cardiac pacing -- Periodicals; Electrophysiology -- Periodicals; 617.4120645
• DOI: 10.1111/pace.13296
• Languages: English
• ISSNs: 0147-8389

Abstract

Abstract: Since its initial description by Jervell and Lange‐Nielsen in 1957, the congenital long QT syndrome (LQTS) has been the most investigated cardiac ion channelopathy. Although congenital LQTS continues to remain the domain of cardiologists, cardiac electrophysiologists, and specialized centers, the by far more frequent acquired drug‐induced LQTS is the domain of all physicians and other members of the health care team who are required to make therapeutic decisions. This report will review the electrophysiological mechanisms of LQTS and torsade de pointes, electrocardiographic characteristics of acquired LQTS, its clinical presentation, management, and future directions in the field.