ADAMTS-5 inhibitor GLPG1972, a potential new treatment in osteoarthritis, shows favorable safety, pharmacokinetics and pharmacodynamics in healthy subjects. (April 2018) - van der Aar, E.M.; Desrivot, J.; Fagard, L.; Amantini, D.; Larsson, S.; Struglics, A.; Lohmander, S.; Vanhoutte, F.; Dupont, S.