Neutrophil–Lymphocyte Ratio and Platelet–Lymphocyte Ratio Combination Can Predict Prognosis in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. (May 2015)

• Record Type: Journal Article
• Authors: Çiçek, Gökhan; Açıkgoz, Sadık Kadri; Bozbay, Mehmet; Altay, Servet; Uğur, Murat; Uluganyan, Mahmut; Uyarel, Huseyin
• Is Part Of: Angiology. Volume 66:Number 5(2015)
• Page Start: 441
• Page End: 447
• Publication Date: 2015-05
• Subjects: acute ST-segment elevation myocardial infarction -- primary angioplasty -- neutrophil–lymphocyte ratio -- platelet–lymphocyte ratio; Blood-vessels -- Diseases -- Periodicals; Cardiovascular system -- Diseases -- Periodicals; 616.13005
• DOI: 10.1177/0003319714535970
• Languages: English
• ISSNs: 0003-3197

Abstract

We assessed the effect of combination of neutrophil–lymphocyte ratio (NLR) and platelet–lymphocyte ratio (PLR) in predicting in-hospital and long-term mortality in patients (n = 2518) undergoing primary percutaneous coronary intervention (pPCI). Cutoff values for NLR and PLR were calculated with receiver–operating characteristic (ROC) curves. If both PLR and NLR were above the threshold, patients were classified as "high risk." If either PLR or NLR was above the threshold individually, patients were classified as "intermediate risk." High-risk (n = 693) and intermediate-risk (n = 545) groups had higher in-hospital and long-term mortality (7.2 4% vs 0.7%, P < .001; 14.1, 9.5% vs 4.5%, P < .001, respectively). Classifying patients into intermediate-risk group (hazards ratio [HR]: 1.492, 95% confidence interval [CI]: 1.022-2.178, P = .038) and high-risk group (HR: 1.845, 95% CI: 1.313-2.594, P < .001) was an independent predictor of in-hospital and long-term mortality. The combination of PLR and NLR can be useful for the prediction of in-hospital and long-term mortality in patients undergoing pPCI.