Successful resolution of hyperammonemia following hematopoietic cell transplantation with directed treatment of Ureaplasma parvum infection. Issue 2 (12th February 2018)

• Record Type: Journal Article
• Authors: Graetz, Riley; Meyer, Robyn; Shehab, Kareem; Katsanis, Emmanuel
• Is Part Of: Transplant infectious disease. Volume 20:Issue 2(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-02-12
• Subjects: hematopoietic cell transplantation -- hyperammonemia -- Ureaplasma parvum; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12839
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: Hyperammonemia following hematopoietic cell transplantation (HCT) has been characterized as idiopathic and is associated with a very high mortality. A causal relationship between Ureaplasma infection and hyperammonemia in immunocompromised lung transplant recipients has recently been described. We document the first case of hyperammonemia following HCT associated with Ureaplasma parvum . The initiation of appropriate antibiotics resulted in rapid resolution of hyperammonemic encephalopathy and eradication of the implicating organism.