The Effect of Dexmedetomidine on Outcomes of Cardiac Surgery in Elderly Patients. Issue 2 (April 2017)

• Record Type: Journal Article
• Authors: Cheng, H.; Li, Z.; Young, N.; Boyd, D.; Atkins, Z.; Ji, F.; Liu, H.
• Is Part Of: Survey of anesthesiology. Volume 61:Issue 2(2017)
• Publication Date: 2017-04
• Subjects: Anesthesiology -- Periodicals; 617.96
• DOI: 10.1097/SA.0000000000000297
• Languages: English
• ISSNs: 0039-6206

Abstract

Abstract : (Abstracted from J Cardiothorac Vasc Anesth, 30(6):1502–1508, 2016) The purpose of this retrospective investigation was to study the effects of the perioperative use of dexmedetomidine (Dex) on outcomes in elderly patients undergoing cardiac surgery. Dexmedetomidine, a highly selective α2 -adrenergic agonist, controls the activity of the sympathetic nervous system by binding to the α2 -receptors present in both the central and peripheral nervous systems and inhibiting the release of norepinephrine, thus modulating sympathetic activity.