Low-Dose Butorphanol Alleviates Remifentanil-Induced Hyperalgesia in Patients Undergoing Laparoscopic Cholecystectomy. Issue 2 (April 2017)

• Record Type: Journal Article
• Authors: Kong, M.; Yang, L.; Li, J.; Zhong, Z.; Cheng, Y.; Wu, Z.; Guo, R.
• Is Part Of: Survey of anesthesiology. Volume 61:Issue 2(2017)
• Publication Date: 2017-04
• Subjects: Anesthesiology -- Periodicals; 617.96
• DOI: 10.1097/01.sa.0000515835.23667.f6
• Languages: English
• ISSNs: 0039-6206

Abstract

Abstract : (Abstracted from J Clin Anesth, 34:41–45, 2016) The objective of this randomized, double-blind clinical trial was to test the hypothesis that low-dose butorphanol can attenuate hyperalgesia induced by high-dose remifentanil infusions in patients undergoing laparoscopic cholecystectomy. Remifentanil, a widely used synthetic opioid, is a potent agonist at the mu-opioid receptor (MOR) and has a short duration of action.