Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial. Issue 3 (March 2018)

• Record Type: Journal Article
• Authors: Laptook, Abbot R.; Shankaran, Seetha; Tyson, Jon E.; Munoz, Breda; Bell, Edward F.; Goldberg, Ronald N.; Parikh, Nehal A.; Ambalavanan, Namasivayam; Pedroza, Claudia; Pappas, Athina; Das, Abhik; Chaudhary, Aasma S.; Ehrenkranz, Richard A.; Hensman, Angelita M.; Van Meurs, Krisa P.; Chalak, Lina F.; Hamrick, Shannon E. G.; Sokol, Gregory M.; Walsh, Michele C.; Poindexter, Brenda B.; Faix, Roger G.; Watterberg, Kristi L.; Frantz, Ivan D.; Guillet, Ronnie; Devaskar, Uday; Truog, William E.; Chock, Valerie Y.; Wyckoff, Myra H.; McGowan, Elisabeth C.; Carlton, David P.; Harmon, Heidi M.; Brumbaugh, Jane E.; Cotten, C. Michael; Sánchez, Pablo J.; Hibbs, Anna Maria; Higgins, Rosemary D.;
• Is Part Of: Obstetrical & gynecological survey. Volume 73:Issue 3(2018)
• Publication Date: 2018-03
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Surgery -- Periodicals; 618
• DOI: 10.1097/01.ogx.0000531330.03991.1a
• Languages: English
• ISSNs: 0029-7828

Abstract

Abstract : (Abstracted from JAMA 2017;318(16):1550–1560) Hypoxic-ischemic neonatal encephalopathy can cause mortality and devastating lifelong cerebral palsy, neurosensory deficits, and cognitive impairments in neonates. Therapeutic hypothermia initiated within 6 hours after birth has been found to reduce the risk of death or disability at 18 months for hypoxic-ischemic encephalopathy.