Exercise has the guts: How physical activity may positively modulate gut microbiota in chronic and immune-based diseases. Issue 4 (April 2018)

• Record Type: Journal Article
• Authors: Codella, Roberto; Luzi, Livio; Terruzzi, Ileana
• Is Part Of: Digestive and liver disease. Volume 50:Issue 4(2018)
• Page Start: 331
• Page End: 341
• Publication Date: 2018-04
• Subjects: Exercise -- Gut microbiota -- Type 1 diabetes; Digestive organs -- Diseases -- Periodicals; Liver -- Diseases -- Periodicals; 616.33005
• DOI: 10.1016/j.dld.2017.11.016
• Languages: English
• ISSNs: 1590-8658

Abstract

Abstract: Limited animal and human research findings suggests that exercise might have a beneficial role for health gut. Cardiorespiratory fitness correlates with health-associated gut parameters such as taxonomic diversity and richness. Physical exercise may augment intestinal microbial diversity through several mechanisms including promotion of an anti-inflammatory state. Disease-associated microbial functions were linked to distinct taxa in previous studies of familial type 1 diabetes mellitus (T1D). An integrated multi-approach in the study of T1D, including physical exercise, is advocated. The present review explores how exercise might modulate gut microbiota and microbiome characteristics in chronic and immune-based diseases, given the demonstrated relationship between gut function and human health.