Boston Type I Keratoprosthesis Implantation Following Autologous Submandibular Gland Transplantation for End Stage Ocular Surface Disorders. (3rd April 2018)

• Record Type: Journal Article
• Authors: Gu, Jianjun; Zhai, Jiajie; Liao, Guiqing; Chen, Jiaqi
• Is Part Of: Ocular immunology and inflammation. Volume 26:Number 3(2018)
• Page Start: 452
• Page End: 455
• Publication Date: 2018-04-03
• Subjects: Autologous submandibular gland transplantation -- Boston keratoprosthesis -- dry eye -- Stevens–Johnson syndrome; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2016.1234624
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose : To describe the results of Boston keratoprosthesis implantation in a patient with Stevens–Johnson syndrome following autologous submandibular gland transplantation. Design : Observational case report. Methods : We report the case of a man diagnosed with Stevens–Johnson syndrome. Autologous submandibular gland transplantation was performed in the right eye in 2008 to ameliorate tear film deficiency. Due to the improvement in the microenvironment of the ocular surface, Boston keratoprosthesis implantation was performed in the right eye in 2011. Results : He maintained a VA of 20/100 for 12 months. At the last follow-up visit (54 months), his VA had declined to finger count level due to de novo glaucoma, which was treated with glaucoma drainage device implantation, cyclophotocoagulation and topical anti-glaucoma medications. Conclusions : The procedures described provide patients with end-stage ocular surface disease an option to lessen the severity of keratoconjunctivitis sicca and to regain their VA.