A benzoic acid terpyridine-based cyclometalated iridium(iii) complex as a two-photon fluorescence probe for imaging nuclear histidine. Issue 30 (29th March 2018) - Zhang, Qiong
Abstract : A series of two-photon active cyclometalated iridium(iii ) complexes (Ir1, Ir2 andIr3 ) were designed. Abstract : A series of two-photon active cyclometalated iridium(iii ) complexes (Ir1, Ir2 andIr3 ) were designed.Ir1 with a two-photon action cross-section of 40 GM in the NIR region has been developed for targeting intracellular histidine. Two-photon micrographs showed thatIr1 could rapidly and selectively light up the nucleus in both fixed and live cells and is capable of displaying nuclear histidine distribution in ultra-detail using a super resolution (SR) technique under stimulated emission depletion (STED) microscopy.