Deacetylation of mitofusin-2 by sirtuin-1: A critical event in cell survival after ischemia. (3rd March 2016)
- Record Type:
- Journal Article
- Title:
- Deacetylation of mitofusin-2 by sirtuin-1: A critical event in cell survival after ischemia. (3rd March 2016)
- Main Title:
- Deacetylation of mitofusin-2 by sirtuin-1: A critical event in cell survival after ischemia
- Authors:
- Lee, Sooyeon
Go, Kristina L.
Kim, Jae-Sung - Abstract:
- ABSTRACT: Sirtuin-1 (SIRT1) is associated with longevity and cell survival. Recently, we unveiled a new role of SIRT1 in hepatic ischemia/reperfusion (I/R) injury and identified a novel interaction between SIRT1 and mitochondrial outer membrane protein mitofusin-2 (MFN2), in which SIRT1-dependent deacetylation of MFN2 regulates mitochondria and autophagy in the liver.
- Is Part Of:
- Molecular & cellular oncology. Volume 3:Number 2(2016)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 3:Number 2(2016)
- Issue Display:
- Volume 3, Issue 2 (2016)
- Year:
- 2016
- Volume:
- 3
- Issue:
- 2
- Issue Sort Value:
- 2016-0003-0002-0000
- Page Start:
- Page End:
- Publication Date:
- 2016-03-03
- Subjects:
- Autophagy -- ischemia/reperfusion -- mitochondria -- mitofusin 2 -- sirtuin 1
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2015.1087452 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 6287.xml