18F-FDG PET/CT in Anti-LGI1 Encephalitis: Initial and Follow-Up Findings. (February 2015)

• Record Type: Journal Article
• Authors: Park, Sohyun; Choi, Hongyoon; Cheon, Gi Jeong; Wook Kang, Keon; Lee, Dong Soo
• Is Part Of: Clinical nuclear medicine. Volume 40:Number 2(2015)
• Publication Date: 2015-02
• Subjects: Anti-LGI1 encephalitis -- 18F-FDG PET -- autoimmune encephalitis; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000000546
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Anti-LGI1 encephalitis is a subgroup of autoimmune encephalitis, characterized by memory impairments, seizures, and behavioral problems. The diagnosis can be made by clinical manifestation with a help of serum autoantibody test. There was lack of imaging studies to evaluate and monitor the disease activity by anatomical and functional information. Here, we report serial 18 F-FDG PET/CT findings in a patient with anti-LGI1 encephalitis. Intense 18 F-FDG uptake was initially noted in bilateral limbic system at active disease status, and then decreased and eventually normalized according to the clinical improvement after treatment. 18 F-FDG PET/CT can be used to evaluate treatment response of encephalitis.