Vertebral Hemangiomas and Their Correlation With Other Pathologies. Issue 8 (April 2016)

• Record Type: Journal Article
• Authors: Slon, Viviane; Peled, Nathan; Abbas, Janan; Stein, Dan; Cohen, Haim; Hershkovitz, Israel
• Is Part Of: Spine. Volume 41:Issue 8(2016)
• Publication Date: 2016-04
• Subjects: back pain -- diabetes -- disc lesions -- hemangiomas -- osteophytosis -- osteoporosis -- Schmorl's nodes -- spinal trauma -- spine imaging -- vascular tumor; Spine -- Abnormalities -- Periodicals; Spine -- Diseases -- Periodicals; Spine -- Surgery -- Periodicals; 616.73005
• DOI: 10.1097/BRS.0000000000001464
• Languages: English
• ISSNs: 0362-2436

Abstract

Abstract : Study Design: This cross-sectional study was carried out on 196 adults (98 men and 98 women), aged between 18 and 91 years. Objective: To examine whether vertebral hemangiomas (VHs) are associated with other spinal pathologies, metabolic diseases, cardiovascular diseases, cancer and past trauma, to shed light on their possible pathophysiology. Summary of Background Data: VHs are the most common form of benign tumors in the spine. Their association with spinal and systemic pathologies has not yet been systematically studied. Methods: Clinical data were gathered from full spine CT scans and medical records. Results: VHs were significantly associated with disc lesions ( P = 0.004), past trauma ( P = 0.037), diabetes (χ 2 = 5.179, P = 0.023), cardio-vascular diseases (χ 2 = 8.625, P = 0.003), and cancer (χ 2 = 5.820, P = 0.016), but not with obesity. Only medium-large size VHs were significantly associated with osteoporosis (χ 2 = 6.695, P = 0.010). Conclusion: The pattern of diseases related to VHs suggests a common cause for VH, namely, a disruption of vascular flow in the microvessels (accompanied by endothelium damage) within the vertebral body, eventually resulting in hypervascularization. Level of Evidence: 4