Tumor Heterogeneity: An Important Determinant for Efficacy and Safety in Nanoparticle Anticancer Gene Therapy. Issue 5 (May 2018)
- Record Type:
- Journal Article
- Title:
- Tumor Heterogeneity: An Important Determinant for Efficacy and Safety in Nanoparticle Anticancer Gene Therapy. Issue 5 (May 2018)
- Main Title:
- Tumor Heterogeneity: An Important Determinant for Efficacy and Safety in Nanoparticle Anticancer Gene Therapy
- Authors:
- Suresh, P.K.
- Abstract:
- Abstract : Models of tumor heterogeneity should mimic perfusion in the tumor mass and consider cancer stem cell hierarchy and convertibility. Other important factors include epigenomic alterations, enhanced permeation and retention effects, and the reticuloendothelial system. New stimuli-responsive delivery systems, active targeting-based methods, and corona characterization strategies can deliver genes more precisely.
- Is Part Of:
- Trends in biotechnology. Volume 36:Issue 5(2018)
- Journal:
- Trends in biotechnology
- Issue:
- Volume 36:Issue 5(2018)
- Issue Display:
- Volume 36, Issue 5 (2018)
- Year:
- 2018
- Volume:
- 36
- Issue:
- 5
- Issue Sort Value:
- 2018-0036-0005-0000
- Page Start:
- 476
- Page End:
- 477
- Publication Date:
- 2018-05
- Subjects:
- Biotechnology -- Periodicals
Biochemical engineering -- Periodicals
Genetic engineering -- Periodicals
Industrial microbiology -- Periodicals
660.605 - Journal URLs:
- http://www.sciencedirect.com/science/journal/01677799 ↗
http://www.elsevier.com/journals ↗ - DOI:
- 10.1016/j.tibtech.2018.02.005 ↗
- Languages:
- English
- ISSNs:
- 0167-7799
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 9049.547000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6253.xml