Three-component solvent-free synthesis of fluorine substituted bicyclic pyridines. Issue 16 (22nd April 2015)
- Record Type:
- Journal Article
- Title:
- Three-component solvent-free synthesis of fluorine substituted bicyclic pyridines. Issue 16 (22nd April 2015)
- Main Title:
- Three-component solvent-free synthesis of fluorine substituted bicyclic pyridines
- Authors:
- Zhu, Dan-Dan
Chen, Xue-Bing
Huang, Rong
Yan, Sheng-Jiao
Lin, Jun - Abstract:
- Abstract: A concise and efficient one-pot three-component synthesis of structurally diverse fluorine substituted bicyclic pyridines was constructed by simply refluxing a mixture of different types of heterocyclic ketene aminals, triethoxymethane, and fluorine-containing methylene compounds under solvent-free and catalyst-free conditions. These bicyclic pyridines are promising candidates for drug discovery; consequently, a library of fluorine substituted bicyclic pyridines was rapidly constructed in 79%–93% yields. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 71:Issue 16(2015)
- Journal:
- Tetrahedron
- Issue:
- Volume 71:Issue 16(2015)
- Issue Display:
- Volume 71, Issue 16 (2015)
- Year:
- 2015
- Volume:
- 71
- Issue:
- 16
- Issue Sort Value:
- 2015-0071-0016-0000
- Page Start:
- 2363
- Page End:
- 2368
- Publication Date:
- 2015-04-22
- Subjects:
- Three-component -- Solvent-free -- Fluorine substituted -- Bicyclic pyridines
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2015.03.006 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6255.xml