SURMOF induced polymorphism and crystal morphological engineering of acetaminophen polymorphs: advantage of heterogeneous nucleation. Issue 15 (28th March 2018)

• Record Type: Journal Article
• Authors: Bolla, Geetha; Myerson, Allan S.
• Is Part Of: CrystEngComm. Volume 20:Issue 15(2018)
• Page Start: 2084
• Page End: 2088
• Publication Date: 2018-03-28
• Subjects: Crystals -- Periodicals; Crystal growth -- Periodicals; Crystallography -- Periodicals; Cristaux -- Périodiques; Cristaux -- Croissance -- Périodiques; Cristallographie -- Périodiques; 548
• DOI: 10.1039/c8ce00272j
• Languages: English
• ISSNs: 1466-8033

Abstract

Abstract : Surface metal organic framework substrates were engineered as heterogeneous surfaces and the importance of these designed surfaces towards polymorphs and morphological engineering was discussed for the first time. Abstract : Self-assembled monolayers are extended to SURMOFs as template hetero surfaces using a basic HKUST-1 MOF. The concept of MOF induced polymorphism with morphological engineering adapted to crystal engineering has shown to have the advantage of heterogeneous nucleation. The substrates are used to study the nucleation and growth of acetaminophen, and have resulted in metastable polymorphs which are of a desirable form with block morphology.