Computational model of visual hallucination in dementia with Lewy bodies. (February 2015)

• Record Type: Journal Article
• Authors: Tsukada, Hiromichi; Fujii, Hiroshi; Aihara, Kazuyuki; Tsuda, Ichiro
• Is Part Of: Neural networks. Volume 62(2015:Feb.)
• Page Start: 73
• Page End: 82
• Publication Date: 2015-02
• Subjects: Dementia with Lewy bodies -- Visual hallucination -- Conduction disturbance -- Top-down facilitation -- Object identity -- Scene gist; Neural computers -- Periodicals; Neural networks (Computer science) -- Periodicals; Neural networks (Neurobiology) -- Periodicals; Nervous System -- Periodicals; Ordinateurs neuronaux -- Périodiques; Réseaux neuronaux (Informatique) -- Périodiques; Réseaux neuronaux (Neurobiologie) -- Périodiques; Neural computers; Neural networks (Computer science); Neural networks (Neurobiology); Periodicals; 006.32
• DOI: 10.1016/j.neunet.2014.09.001
• Languages: English
• ISSNs: 0893-6080

Abstract

Abstract: Patients with dementia with Lewy bodies (DLB) frequently experience visual hallucination (VH), which has been aptly described as people seeing things that are not there. The distinctive character of VH in DLB necessitates a new theory of visual cognition. We have conducted a series of studies with the aim to understand the mechanism of this dysfunction of the cognitive system. We have proposed that if we view the disease from the internal mechanism of neurocognitive processes, and if also take into consideration recent experimental data on conduction abnormality, at least some of the symptoms can be understood within the framework of network (or disconnection) syndromes. This paper describes the problem from a computational aspect and tries to determine whether conduction disturbances in a computational model can in fact produce a "computational" hallucination under appropriate assumptions.