Clinical Complications in Outpatient Myelodysplastic Syndromes. (February 2015)

• Record Type: Journal Article
• Authors: Tendas, Andrea; Niscola, Pasquale; Cupelli, Luca; Scaramucci, Laura; Giovannini, Marco; Piccioni, Daniela; Dentamaro, Teresa; Perrotti, Alessio Pio; de Fabritiis, Paolo
• Is Part Of: Home health care management & practice. Volume 27:Number 1(2015:Feb.)
• Page Start: 18
• Page End: 23
• Publication Date: 2015-02
• Subjects: home outpatient care -- adverse effects -- complications -- infections -- myelodysplastic syndromes -- quality of life; Home care services -- Periodicals; 649
• DOI: 10.1177/1084822314534259
• Languages: English
• ISSNs: 1084-8223

Abstract

The aim of our research is to evaluate the rate, the type, the severity, the causative factors, and the pathogenesis of complications during the course of myelodysplastic syndromes (MDS). Complications among MDS patients on outpatient management were prospectively recorded and classified. During an 18-month observation period, complications emerging in 48 outpatients with MDS, of whom 15 (31%) were on active treatment and 33 (69%) were receiving best supportive care alone, were recorded and analyzed. Out of 48 patients (median age, 72 years), 34 (71%) experienced complications; a total number of 92 events were recorded; most frequently observed events were infections (43 events, 47%) and bleeding (11 events, 12%). Complications are a frequent issue in MDS; preventive measures should be directed toward the most frequently observed complications.