Articular cartilage from osteoarthritis patients shows extracellular matrix remodeling over the course of treatment with Sprifermin (recombinanant human fibroblast growth factor 18). (April 2018) - Reker, D.; Thudium, C.S.; Sofie Siebuhr, A.; Gantzel, T.; Ladel, C.; Michaelis, M.; Karsdal, M.A.; Gigout, A.; Bay-Jensen, A.C.