Positive peritoneal fluid fungal cultures in postoperative peritonitis after bariatric surgery. (September 2015)

• Record Type: Journal Article
• Authors: Zappella, N.; Desmard, M.; Chochillon, C.; Ribeiro-Parenti, L.; Houze, S.; Marmuse, J.-P.; Montravers, P.
• Is Part Of: Clinical microbiology and infection. Volume 21:Number 9(2015:Sep.)
• Page Start: 853.e1
• Page End: 853.e3
• Publication Date: 2015-09
• Subjects: Antifungal therapy -- bariatric surgery -- fungal peritonitis -- morbid obesity -- postoperative peritonitis; Medical microbiology -- Periodicals; Diagnostic microbiology -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 616.01
• DOI: 10.1016/j.cmi.2015.05.024
• Languages: English
• ISSNs: 1198-743X

Abstract

Abstract: Postoperative peritonitis (POP) is a common surgical complication after bariatric surgery (BS). We assessed the importance of positive fungal cultures in these cases of POP admitted to the intensive care unit. Clinical features and outcome were compared in 25 (41%) Candida -positive patients (6 (22%) fluconazole-resistant Candida glabrata ) and 36 patients without Candida infection. Candida infections were more commonly isolated in late-onset peritonitis and were often associated with multidrug-resistant bacteria. Risk factors for intensive care unit mortality (19.6%) were diabetes and superobesity. Candida infections, including fluconazole-resistant strains, are common in POP after BS. These data encourage the empirical use of a broad-spectrum antifungal agent.