A 36-year-old patient with a multinodular lesion in the left temporal lobe. (April 2018)

• Record Type: Journal Article
• Authors: Gaudino, Simona; Sturiale, Carmelo Lucio; Ruberto, Emanuela; Colosimo, Cesare; Olivi, Alessandro; Gessi, Marco
• Is Part Of: Journal of clinical neuroscience. Volume 50(2018)
• Page Start: 100
• Page End: 101
• Publication Date: 2018-04
• Subjects: Multinodular and vacuolating neuronal tumor -- MVNT -- Epilepsy -- Glioneuronal tumor -- Central nervous system; Brain -- Surgery -- Periodicals; Neurosciences -- Periodicals; Nervous system -- Surgery -- Periodicals; Brain -- surgery -- Periodicals; Neurosurgical Procedures -- Periodicals; Neurosciences -- Periodicals; Electronic journals; 616.8
• DOI: 10.1016/j.jocn.2018.01.026
• Languages: English
• ISSNs: 0967-5868

Abstract

Highlights: A 36-year-old female with right-sided focal motor seizures and absence. MRI scan showed multiple nodules in white matter of left superior temporal gyrus. The lesion was a multinodular and vacuolating neuronal tumor (MVNT) of the CNS. Abstract: A 36-year-old female patient was referred to our hospital for a six-months clinical history of episodes of right-sided focal motor seizures and absence. MRI scan showed a multi-nodular lesion in the subcortical white matter of left superior temporal gyrus. After a complete resection, the neuropathological examination revealed a lesion with marked cell vacuolation which was composed of neuroepithelial cells ranging from small to medium sized elements to larger, neuron-like cells, occasionally bi-nucleated. The neuropathological features of the lesion were compatible with the diagnosis of multinodular and vacuolating neuronal tumor (MVNT) of the CNS. MVNT is very rare, recently described entity among the large spectrum of glioneuronal tumors. It is characterized by benign clinical behavior and neurosurgical resection usually provide control of disease.