Alkaline earth metal catalyzed cascade, one-pot, solvent-free, and scalable synthesis of pyranocoumarins and benzo[b]pyrans. Issue 13 (25th March 2015)

• Record Type: Journal Article
• Authors: Yaragorla, Srinivasarao; Saini, Pyare Lal; Singh, Garima
• Is Part Of: Tetrahedron letters. Volume 56:Issue 13(2015)
• Page Start: 1649
• Page End: 1653
• Publication Date: 2015-03-25
• Subjects: Pyranocoumarins -- Benzopyrans -- Ca(II) catalysis -- Solvent-free synthesis -- Cascade synthesis; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.02.023
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: Ca(OTf)2 catalyzed, cascade, one-pot, conjugate addition and annulation of various nucleophiles to the α, β-unsaturated carbonyl compounds for the synthesis of biologically potent pyranocoumarins and benzo[ b ]pyrans has been illustrated. This one-pot, solvent-free, green-synthesis employs simple reaction conditions, with high yields and endures the substrate diversity.